Unsolved Medical Mysteries: Explaining the Unexplainable · Brandy Schillace, The Great Courses

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In the 1630s, children in southern France described a chilling sensation: worms wriggling beneath their skin. Were these parasitic infestations or figments of their imagination? Centuries earlier, a 14th-century French king insisted his body was made of glass, fearing a single misstep could shatter him. And today, doctors encounter baffling conditions like stiff person syndrome, fibromyalgia, long Covid, and the common migraine.

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